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Autonomic nervous system and endocrine system response to upper or lower cervical spine mobilization in males with persistent post-concussion symptoms: a proof-of-concept trial.

Gerard FarrellCathy M ChappleEwan KennedyMatthew Reily-BellKesava SampathAngela Spontelli GisselmanChad E CookRajesh G KatareSteve Tumilty
Published in: The Journal of manual & manipulative therapy (2024)
The results of this trial provide preliminary evidence for cervical spine mobilizations to differentially modulate components of the stress response at specific time points. Understanding the mechanisms of the effect of cervical spine mobilizations on the stress response provides a novel rationale for selecting cervical spine mobilizations to rehabilitate individuals with PPCS.
Keyphrases
  • phase iii
  • clinical trial
  • study protocol
  • phase ii
  • open label
  • heart rate
  • sleep quality
  • double blind