Direct and indirect effects of COVID-19 on perinatal outcomes in low- and middle-income countries.
Felisita Tupou RatuKathleen RyanNetsanet Workneh GidiIlisapeci VeretiTsinuel GirmaJeremy OatsIngrid BucensAlexandra RobinsonClaire von MollendorfFiona M RussellPublished in: Gates open research (2021)
Similar to previous outbreaks, the coronavirus disease 2019 (COVID-19) pandemic will have both direct and indirect effects on perinatal outcomes, especially in low- and middle-income countries. Limited data on the direct impact of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection during pregnancy shows women who are Black, obese and with co-morbidities are at higher risk of hospitalisation due to COVID-19. Younger age groups in Africa and South Asia have shown increased COVID-19 mortality. Indigenous pregnant women in Pacific Island countries are likely to be high risk for severe outcomes from COVID-19 due to high rates of diabetes and obesity. It is important to involve pregnant women in research, especially with regards to vaccine development and therapeutics.
Keyphrases
- coronavirus disease
- respiratory syndrome coronavirus
- pregnant women
- sars cov
- type diabetes
- weight loss
- metabolic syndrome
- pregnancy outcomes
- cardiovascular disease
- adipose tissue
- small molecule
- glycemic control
- coronary artery disease
- body mass index
- polycystic ovary syndrome
- big data
- machine learning
- physical activity
- skeletal muscle