Prediagnosis aspirin use, DNA methylation, and mortality after breast cancer: A population-based study.

Tengteng WangLauren E McCulloughAlexandra J WhitePatrick T BradshawXinran XuYoon Hee ChoMary Beth TerrySusan L TeitelbaumAlfred I NeugutRegina M SantellaJia ChenMarilie D Gammon

Published in: Cancer (2019)

The current study suggests that the LINE-1 global methylation and promoter methylation of BRCA1 and PR in tumor may interact with aspirin use to influence mortality after breast cancer.

Keyphrases

dna methylation
genome wide
low dose
gene expression
cardiovascular events
antiplatelet therapy
breast cancer risk
copy number
type diabetes
cardiovascular disease
percutaneous coronary intervention
atrial fibrillation