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Blockade of thromboxane A2 signaling attenuates ethanol-induced myocardial inflammatory response in mice.

Weilun AiCarol A CaseyParas Kumar MishraYazen AlnoutiSohel DariaViswanathan Saraswathi
Published in: Alcohol, clinical & experimental research (2024)
This study demonstrates that ethanol promotes the NLRP3 signaling pathway within the myocardium, leading to a pro-inflammatory milieu that potentially initiates early myocardial remodeling, and TP-R antagonism attenuates this effect.
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