Subtypes and location of (juxta)cortical lesions relate to cognitive dysfunction in people with multiple sclerosis.
Eva A KrijnenRose-Marie KouwenhovenSamantha NoteboomFrederik BarkhofBernard Mj UitdehaagEric C KlawiterMartijn D SteenwijkMenno Michiel SchoonheimIsmail KoubiyrPublished in: Multiple sclerosis (Houndmills, Basingstoke, England) (2024)
In CI-MS, leukocortical lesions predominate, whereas intracortical lesions distinguish cognitive groups. Lesions' grey matter (GM) involvement might be decisive for cognition in MS, surpassing overall disease burden.