Human cultured IMR-32 neuronal-like and U87 glial-like cells have different patterns of toxicity under fluoride exposure.

Bruna PutyLeonardo Oliveira BittencourtIago Cesar NogueiraMarília Afonso Rabelo BuzalafEdivaldo Herculano Correia de Oliveira Rafael Rodrigues Lima

Published in: PloS one (2021)

Our results suggest an important differential behavior of the distinct types of cells exposed to the different fluoride concentrations, pointing that the U87 glial-like cells as more susceptible to damage triggered by this ion.

Keyphrases

endothelial cells
induced apoptosis
drinking water
oxidative stress
neuropathic pain
cell cycle arrest
induced pluripotent stem cells
spinal cord injury
signaling pathway
blood brain barrier
brain injury
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