Impact of red blood cell distribution width and mean platelet volume in patients with ST-segment elevation myocardial infarction.
Toshiaki EbinaShiori TochiharaMai OkazakiKazuyo KoikeYuko TsutoMegumi TayamaYukiko TakanamiHaruka HiroseMutsuo HoriiKozo OkadaYasushi MatsuzawaNobuhiko MaejimaNoriaki IwahashiKiyoshi HibiMasami KosugeKouichi TamuraKazuo KimuraPublished in: Heart and vessels (2021)
The complete blood cell count is one of the most frequently ordered laboratory tests, and many parameters, including red blood cell distribution width (RDW) and mean platelet volume (MPV), are available. The purpose of this study was to investigate the usefulness of the combination of RDW and MPV in patients with ST-segment elevation myocardial infarction (STEMI). Patients with STEMI who underwent primary percutaneous coronary intervention were retrospectively enrolled (n = 229). The association between RDW as well as MPV and cardiovascular events was investigated. The median age was 67 years, and males made up 85% of the sample. Median RDW was 13.6%, and median MPV was 8.2 fL. During a median follow-up period of 528 days (IQR 331.5-920.5), 41 patients died or experienced major adverse cardiac and cerebrovascular events (MACCEs). Patients with RDW ≧ 13.7% had more deaths or MACCEs with marginal significance (p = 0.0799). Patients with MPV ≧ 8.3 fL had significantly more deaths or MACCEs (p = 0.0283). Patients with RDW ≧ 13.7% and MPV ≧ 8.3 fL had significantly more deaths or MACCEs (p = 0.0185). MPV was significantly associated with death or adverse events in patients with STEMI who were treated with primary PCI. RDW had only a weak association with death or adverse events. The results of the combination of MPV and RDW were similar to those of MPV.
Keyphrases
- st segment elevation myocardial infarction
- percutaneous coronary intervention
- red blood cell
- coronary artery disease
- st elevation myocardial infarction
- acute myocardial infarction
- antiplatelet therapy
- acute coronary syndrome
- cardiovascular events
- coronary artery bypass grafting
- newly diagnosed
- atrial fibrillation
- coronary artery bypass
- cardiovascular disease
- type diabetes
- end stage renal disease
- emergency department
- single cell
- high resolution
- chronic kidney disease
- mesenchymal stem cells
- left ventricular
- heart failure
- stem cells
- bone marrow