Decreased emergence of HIV-1 drug resistance mutations in a cohort of Ugandan women initiating option B+ for PMTCT.
Patrycja MachnowskaAndrea HauserKarolin MeixenbergerBritta AltmannNorbert BannertEva RempisAlexandra SchnackSarah DeckerVera BraunPriscilla BusingyeJohn RubaihayoGundel HarmsStefanie TheuringPublished in: PloS one (2017)
Our findings suggest that the WHO-recommended Option B+ for PMTCT is effective in a cohort of Ugandan HIV-1 positive pregnant women with regard to the low selection rate of DRMs and vertical transmission. Therefore, these results are encouraging for other countries considering the implementation of lifelong cART for all pregnant HIV-1 positive women.
Keyphrases
- hiv positive
- men who have sex with men
- antiretroviral therapy
- south africa
- polycystic ovary syndrome
- hiv testing
- human immunodeficiency virus
- pregnant women
- hiv infected
- pregnancy outcomes
- primary care
- healthcare
- hiv aids
- cervical cancer screening
- breast cancer risk
- metabolic syndrome
- quality improvement
- adipose tissue
- hepatitis c virus