Flavonoids in a crude extract of Catha edulis inhibit rat intestinal contraction via blocking Ca2+ channels.
Tadele NigusseLing ZhangRong WangXiao-Ning WangJing Xin LiChuanyong LiuPublished in: Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society (2019)
The crude extract of Catha edulis has a spasmolytic effect on the rat ileum, which is mediated through blocking Ca2+ channels, and quercetin, kaempferol, and myricetin were found to be the causative compounds.