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Diffuse C-Cells Hyperplasia Is the Source of False Positive Calcitonin Measurement in FNA Washout Fluids of Thyroid Nodules: A Rational Clinical Approach to Avoiding Unnecessary Surgery.

Chiara MuraRossella RodiaSilvia CorriasAntonello CappaiMaria Letizia LaiGian Luigi CanuFabio MedasPietro Giorgio CalòStefano MariottiFrancesco Boi
Published in: Cancers (2024)
Employing the currently proposed cut-off values, false-positive FNA-CT results may be observed in benign/malignant TNs with coexisting diffuse CCH. FNA-CT must therefore be cautiously used in the diagnostic approach for patients with TNs and a slightly increased basal or stimulated serum CT concentration in order to avoid unnecessary surgery.
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