Impact of metformin on the clinical and metabolic parameters of women with polycystic ovary syndrome: a systematic review and meta-analysis of randomised controlled trials.

Mohammed Altigani AbdallaNajeeb ShahHarshal DeshmukhAmirhossein SahebkarLinda ÖstlundhRami H Al-RifaiStephen L AtkinThozhukat Sathyapalan

Published in: Therapeutic advances in endocrinology and metabolism (2022)

In women with PCOS, metformin use has shown a positive impact in reducing body weight, BMI, total testosterone, androstenedione, 17-OHP, LDL-C, fasting blood glucose and increasing the likelihood of pregnancy in women with PCOS.

Keyphrases

blood glucose
polycystic ovary syndrome
body weight
insulin resistance
glycemic control
pregnancy outcomes
blood pressure
body mass index
preterm birth
replacement therapy
type diabetes
adipose tissue
weight gain
pregnant women
physical activity
weight loss
cervical cancer screening