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[CIC-rearranged sarcoma: a case report and literature review].

I V SidorovA S FedorovaE I KonoplevaN P MakarovaA S SharlaiDmitriy Konovalov
Published in: Arkhiv patologii (2023)
CIC -rearranged sarcoma is a rare and extremely aggressive tumor that occurs mainly in soft tissues. Despite the fact that identification of a characteristic genetic rearrangement is necessary to verify the diagnosis, in most cases, the correct diagnosis can be made by comparing histological signs and a characteristic immunophenotype, which greatly speeds up the diagnosis. The article describes a case of CIC- rearranged sarcoma in a 14-year girl with the successful application of the CWS-2009 treatment protocol.
Keyphrases
  • gene expression
  • copy number
  • genome wide
  • dna methylation
  • smoking cessation