An injectable, biodegradable calcium phosphate cement containing poly lactic-co-glycolic acid as a bone substitute in ex vivo human vertebral compression fracture and rabbit bone defect models.

Xin DuanHong-Xing LiaoHua-Zhang ZouZi-Ji ZhangJian-Dong YeWei-Ming Liao

Published in: Connective tissue research (2017)

Our biodegradable CPC/PLGA composite showed good biomechanical properties, cytocompatibility, and osteoconductivity and may represent an ideal bone substitute for future applications.

Keyphrases

bone mineral density
drug delivery
bone regeneration
postmenopausal women
soft tissue
endothelial cells
bone loss
body composition
hyaluronic acid
hip fracture
finite element