Polytrauma in Older Adults Leads to Significantly Increased TIMP-1 Levels in the Early Posttraumatic Period.

Mareen Braunstein Thomas KusmenkovWolf MutschlerChristian Kammerlander Wolfgang Böcker Viktoria Bogner-Flatz

Published in: Journal of immunology research (2020)

The posttraumatic immune response is characterized by significantly higher TIMP-1 levels in older polytrauma patients. This significant association between TIMP-1 levels and patients' age indicates a more extensive immune dysregulation following major trauma in older adults.

Keyphrases

end stage renal disease
immune response
ejection fraction
newly diagnosed
chronic kidney disease
peritoneal dialysis
prognostic factors
toll like receptor
dendritic cells
trauma patients