Sparse canonical correlation to identify breast cancer related genes regulated by copy number aberrations.

Diptavo DuttaAnanda SenJaya Satagopan

Published in: PloS one (2022)

Our findings suggest that sCCA analysis can aggregate weaker associations to identify interpretable and important genes, modules, and clinically consequential pathways.

Keyphrases

copy number
genome wide
mitochondrial dna
dna methylation
gene expression
data analysis
breast cancer risk
genome wide analysis