Sparse canonical correlation to identify breast cancer related genes regulated by copy number aberrations.

Diptavo DuttaAnanda SenJaya Satagopan

Published in: PloS one (2022)

Our findings suggest that sCCA analysis can aggregate weaker associations to identify interpretable and important genes, modules, and clinically consequential pathways.

Keyphrases

copy number
genome wide

mitochondrial dna
dna methylation

gene expression
data analysis

breast cancer risk
genome wide analysis