Sex-specific effects of psychedelics on prepulse inhibition of startle in 129S6/SvEv mice.
Hiba Z VohraJustin M SaundersAlaina M JasterMario de la Fuente RevengaJennifer JimenezAlberto Fernández-TeruelJennifer T WolstenholmePatrick M BeardsleyJavier González-MaesoPublished in: Psychopharmacology (2021)
Our findings highlight a distinct effect of the psychedelic DOI on PPI in 129S6/SvEv mice, suggesting 5-HT2AR-dependent PPI improvement in a paradigm-dependent and sex-dependent manner.