3D image-guided treatment planning for Ruthenium-106 brachytherapy of choroidal melanomas.

Charlotte A Espensen Jens Folke Kiilgaard Kristian Klemp Anita B Gothelf Ane L Appelt Lotte S Fog

Published in: Acta ophthalmologica (2020)

3D treatment planning theoretically allows for improved tumour dose delivery for Ru-106 brachytherapy of choroidal melanomas, resulting in a significant increase in expected tumour control compared to traditional approaches using 2D calculations. The deliverability of optimized plans, and potential increased risk of late complications, will have to be confirmed in future clinical studies.

Keyphrases

high dose
optical coherence tomography
radiation therapy
age related macular degeneration
locally advanced
density functional theory
low dose
optic nerve
molecular dynamics
current status
risk factors
molecular dynamics simulations
squamous cell carcinoma
risk assessment
energy transfer