Targeting ataxia telangiectasia-mutated- and Rad3-related kinase (ATR) in PTEN-deficient breast cancers for personalized therapy.

Nouf Al-SubhiReem AliTarek Abdel-FatahPaul M MoseleyStephen Y T ChanAndrew R GreenIan O EllisEmad A RakhaSrinivasan Madhusudan

Published in: Breast cancer research and treatment (2018)

ATR signalling adversely impact survival in PTEN-deficient breast cancers. ATR inhibition is synthetically lethal in PTEN-deficient TNBC cells.

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