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Synthesis, Computational and Pharmacological Evaluation of 7-(2-(2- (3-(Substituted Phenyl) Acryloyl) Phenoxy) Ethoxy)-4-Methyl-2H-Chromen-2-Ones as CNS Agents.

Sushil KumarAmit Kumar
Published in: Central nervous system agents in medicinal chemistry (2023)
Among the target compounds, the fluoro group containing compound was found to be more potent as compared to the standard drug diazepam.
Keyphrases
  • positron emission tomography
  • molecular docking
  • blood brain barrier
  • anti inflammatory
  • computed tomography
  • adverse drug
  • emergency department
  • drug induced
  • molecular dynamics simulations
  • pet ct