DNA content abnormality frequently develops in the right/proximal colon in patients with primary sclerosing cholangitis and inflammatory bowel disease and is highly predictive of subsequent detection of dysplasia.
Ruth ZhangPeter S RabinovitchAras N MattisGregory Y LauwersWon-Tak ChoiPublished in: Histopathology (2023)
PSC-IBD patients have an increased risk of developing abnormal DNA content in the right/proximal colon, predating the detection of dysplasia.