Long-term antipsychotic use, orthostatic hypotension and falls in older adults with Alzheimer's disease.

Adam H DyerClaire MurphyHelena DolphinLaura MorrisonRobert BriggsBrian LawlorSean P Kennellynull null

Published in: European geriatric medicine (2024)

Even in mild-to-moderate AD, long-term antipsychotic use was associated with ssOH. Both antipsychotic use and ssOH were associated with a greater risk of incident falls/syncope over 18 months. Further attention to optimal prescribing interventions in this cohort is warranted and may involve screening older adults with AD prescribed antipsychotics for both orthostatic symptoms and falls.

Keyphrases

community dwelling
physical activity
primary care
cardiovascular disease
working memory
pulmonary embolism
emergency department
type diabetes
sleep quality
electronic health record