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Blockade of checkpoint receptor PVRIG unleashes anti-tumor immunity of NK cells in murine and human solid tumors.

Yangyang LiYu ZhangGuoshuai CaoXiaodong ZhengCheng SunHaiming WeiZhigang TianWeihua XiaoRui SunHaoyu Sun
Published in: Journal of hematology & oncology (2021)
Our results reveal the importance of NK cells and provide novel knowledge for clinical application of PVRIG-targeted drugs in future.
Keyphrases
  • nk cells
  • endothelial cells
  • dna damage
  • healthcare
  • induced pluripotent stem cells
  • cell cycle
  • cancer therapy
  • cell proliferation
  • dna methylation
  • drug delivery
  • drug induced