Minimally invasive and targeted therapeutic cell delivery to the skin using microneedle devices.
Benedetta GualeniSion A CoulmanD ShahP F EngH AshrafP VescovoG J BlayneyL-D PiveteauO J GuyJ C BirchallPublished in: The British journal of dermatology (2018)
Hollow microneedles provide an innovative and minimally invasive method for delivering functional cells into the skin. Microneedle cell delivery represents a potential new treatment option for cell therapy approaches including skin repigmentation, wound repair, scar and burn remodelling, immune therapies and cancer vaccines.
Keyphrases
- cell therapy
- wound healing
- minimally invasive
- stem cells
- soft tissue
- single cell
- mesenchymal stem cells
- induced apoptosis
- papillary thyroid
- cell cycle arrest
- squamous cell
- squamous cell carcinoma
- oxidative stress
- signaling pathway
- cell proliferation
- combination therapy
- high resolution
- human health
- smoking cessation
- mass spectrometry
- molecularly imprinted
- pi k akt