Treatment outcomes of integrase inhibitors, boosted protease inhibitors and nonnucleoside reverse transcriptase inhibitors in antiretroviral-naïve persons starting treatment.
Amanda MocroftB NeesgardR ZangerleA RiegerA CastagnaV SpagnuoloA AntinoriF C LampeM YouleJ J VehreschildC MussiniV BorghiJ BegovacC DuvivierH F GunthardA RauchJ TiraboschiN ChkhartishviliN BolokadzeF WitJ C WasmuthS De WitC NecsoiC PradierV SvedhemC StephanK PetoumenosH GargesF RogattoL PetersL Ryomnull nullPublished in: HIV medicine (2020)
Differences among ART classes in virological, immunological and clinical outcomes in ART-naïve participants were consistent irrespective of age, immune suppression or VL at ART initiation. While confounding by indication cannot be excluded, this provides reassuring evidence that such subpopulations will equally benefit from contemporary ART.