Characterization of Parkinson's disease using blood-based biomarkers: A multicohort proteomic analysis.
Marijan PosaviMaria E Diaz-OrtizBenjamine LiuChristine R SwansonR Tyler SkrinakPilar Hernandez-ConDefne A AmadoMichelle FullardJacqueline RickAndrew SiderowfDaniel WeintraubLeo McCluskeyJohn Q TrojanowskiRichard B DeweyXuemei HuangAlice S Chen-PlotkinPublished in: PLoS medicine (2019)
In this study, we found that the blood-based biomarkers BSP, OMD, ACY1, and GHR robustly associated with PD across multiple clinical sites. Our findings suggest that biomarkers based on a peripheral blood sample may be developed for both disease characterization and prediction of future disease progression in PD.
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