Optimizing the Diagnostic Strategy to Identify Genetic Abnormalities in Miscarriage.

Jong-Mi LeeSo Young ShinGuk Won KimWoo Jeng KimJeong Ha WieSubeen HongDain KangHayoung ChoiJisook YimYonggoo KimMyung-Shin KimIn Yang Park

Published in: Molecular diagnosis & therapy (2021)

Although conventional karyotyping and FISH are still needed, SNP-array represents the first choice for miscarriage because the technique showed excellent performance in the detection of genetic abnormalities and minimized the probability of testing failure as well as time, costs, and labor.

Keyphrases

genome wide
copy number
dna methylation
high density
high throughput
high resolution
loop mediated isothermal amplification
real time pcr
mass spectrometry
single cell