Optimization of Absolute Coronary Blood Flow Measurements to Assess Microvascular Function: In Vivo Validation of Hyperemia and Higher Infusion Speeds.
Lennert MintenJohan BennettKeir McCutcheonWouter OosterlinckMichiel AlgoetHisao OtsukiKuniaki TakahashiWilliam F FearonChristophe DuboisPublished in: Circulation. Cardiovascular interventions (2024)
Continuous saline infusion of 30 mL/min but not 20 mL/min induced maximal hyperemia. Absolute coronary blood flow measured with saline infusion speeds of 40 to 50 mL/min was not accurate and not safe.