Clinical and Laboratory Factors Related to Seizure and Serotonin Toxicity in Tramadol Intoxication: An Egyptian Study.

Ahmed Amin AliMahmoud Mohamed AbdeshafyKhaled AbdelkawyRamy M ElsabaaFawzy A Elbarbry

Published in: Clinical drug investigation (2023)

Seizure and serotonin toxicity are severe adverse effects of tramadol overdose that occur in high frequency among young Egyptians. High tramadol concentrations in plasma seem to play a key role in prevalence of seizure and serotonin syndrome in tramadol-intoxicated adult Egyptians.

Keyphrases

high frequency
transcranial magnetic stimulation
temporal lobe epilepsy
oxidative stress
risk factors
early onset
emergency department
postoperative pain
young adults
drug induced
oxide nanoparticles