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Declined Humoral Immunity of Kidney Transplant Recipients to SARS-CoV-2 Vaccines.

Waleed H MahallawiWael A AlharbiSultan A AloufiNadir A IbrahimMuntasir M AbdelrahmanBader A AlhomayeedMoutasem Salih AboonqSaeed Awad M AlqahtaniEmad S RajihAbdulaziz M BakhshJillian K Warejko
Published in: Infection and drug resistance (2023)
KTRs' humoral response after SARS-CoV-2 vaccination is dramatically inhibited and wanes. Antibody levels show a significant decline over time in KTRs with hypertension; receiving triple immunosuppressive therapy or steroid-based or antimetabolite-based regimens; receiving mixed mRNA and viral vector vaccines; and with a transplant of >10 years.
Keyphrases
  • sars cov
  • immune response
  • respiratory syndrome coronavirus
  • blood pressure
  • binding protein
  • mesenchymal stem cells