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Drugs Contributing to Anticholinergic Burden and Risk of Fall or Fall-Related Injury among Older Adults with Mild Cognitive Impairment, Dementia and Multiple Chronic Conditions: A Retrospective Cohort Study.

Ariel R GreenLiza M ReiflerElizabeth A BaylissLinda A WeffaldCynthia M Boyd
Published in: Drugs & aging (2019)
The same daily ACB score was associated with a different degree of risk, depending on the ACB ratings of the individual drugs comprising the score. Combinations of level 2 and level 3 drugs had the greatest risk of fall or fall-related injury relative to other individuals with the same daily ACB score. Low-potency anticholinergic drugs taken together modestly increased the hazard of a fall or fall-related injury.
Keyphrases
  • mild cognitive impairment
  • cognitive decline
  • drug induced
  • physical activity
  • breast cancer risk