Predominantly defective CD8 + T cell immunity to SARS-CoV-2 mRNA vaccination in lung transplant recipients.

Ellie TausMichael Y ShinoF Javier IbarrondoMary Ann HausnerChristian HofmannOtto O Yang

Published in: Journal of translational medicine (2023)

T cells, which have key roles both in transplanted organ rejection but also antiviral effector responses. Overcoming this defect will require strategies to enhance vaccine immunogenicity in immunocompromised persons.

Keyphrases

sars cov
respiratory syndrome coronavirus
regulatory t cells
dendritic cells
type iii
respiratory failure
binding protein
african american
coronavirus disease
acute respiratory distress syndrome