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Antimicrobial Activities of New Indole Derivatives Containing 1,2,4-Triazole, 1,3,4-Thiadiazole and Carbothioamide.

Hanif ShirinzadehSibel SuzenNurten AltanlarAndrew D Westwell
Published in: Turkish journal of pharmaceutical sciences (2018)
The compounds possessed a broad spectrum of activity having MIC values of 3.125-50 µg/mL against the tested microorganisms. This study provides valuable evidence that the indole-triazole derivative compound 3d holds significant promise as a novel antibacterial and antifungal lead compound.
Keyphrases
  • staphylococcus aureus
  • candida albicans
  • big data
  • structure activity relationship