Therapeutic efficacy of pH-dependent release formulation of mesalazine on active ulcerative colitis resistant to time-dependent release formulation: analysis of fecal calprotectin concentration.
Kousaku KawashimaShunji IshiharaTakafumi YukiKoji OnishiYoshinori KushiyamaHirofumi FujishiroYouichi MiyaokaMika YukiYoshinori KomazawaTakashi TanimuraHiroki SonoyamaYasumasa TadaRyusaku KusunokiAkihiko OkaNobuhiko FukubaNaoki OshimaIchiro MoriyamaYoshikazu KinoshitaPublished in: BioMed research international (2014)
Our results suggest that pH-5-ASA has clinical efficacy for mildly to moderately active patients with UC in whom time-5-ASA did not successfully induce or maintain remission.