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Evaluating the effect of TLR4-overexpressing on the transcriptome profile in ovine peripheral blood mononuclear cells.
Xiaofei Guo
Jinlong Zhang
Yao Li
Jing Yang
Yihai Li
Chunxiao Dong
Guoshi Liu
Zhengxing Lian
Xiaosheng Zhang
Published in:
Journal of biological research (Thessalonike, Greece) (2020)
The RNA-Seq results revealed that the overexpressed TLR4 in our experiment strengthened the ovine innate immune response by increasing the phagocytosis in PBMC.
Keyphrases
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immune response
rna seq
single cell
toll like receptor
dendritic cells
inflammatory response
nuclear factor
genome wide