A Bedside Method for Measuring Effects of a Sedative Drug on Cerebral Function in Newborn Infants.

Sofie Nilsson Anton TokarievMarjo MetsärantaElisabeth Norman Sampsa Vanhatalo

Published in: Sensors (Basel, Switzerland) (2022)

Cerebral effects of dexmedetomidine as determined by EEG in newborn infants are related to cortical activity prior to DEX administration, indicating that higher brain activity levels (higher rEEG) during baseline links to a more pronounced reduction by DEX. The computational measurements indicate drug effects on both overall cortical activity and cortico-cortical communication. These effects were not evident in visual analysis.

Keyphrases

subarachnoid hemorrhage
drug induced
cardiac surgery
cerebral ischemia
adverse drug
emergency department
brain injury
resting state
electronic health record
high density