Differences in thrombin and plasmin generation potential between East African and Western European adults: The role of genetic and non-genetic factors.

Godfrey S Temba Nadira Vadaq Jun WanVesla KullayaDana HuskensTal PechtMartin JaegerCollins K BoahenVasiliki MatzarakiWieteke BroedersLeo A B JoostenSultana M H FaradzGibson KibikiSaskia MiddeldorpDuccio CavalieriPaolo LionettiPhilip G de GrootJoachim L SchultzeMihai G NeteaVinod KumarBas de Laat Blandina Theophil MmbagaAndre J van der VenMark RoestQuirijn de Mast

Published in: Journal of thrombosis and haemostasis : JTH (2022)

Tanzanians have an enhanced TG and PG potential compared to Dutch individuals, which may relate to differences in inflammation, genetics and diet. These observations highlight the importance of better understanding of the geographic variability in coagulation across populations.

Keyphrases

genome wide
oxidative stress
physical activity
copy number
human health
south africa
weight loss
gene expression
dna methylation
climate change