MGA deletion leads to Richter's transformation via modulation of mitochondrial OXPHOS.

Prajish IyerBo ZhangTingting LiuMeiling JinKevyn HartJibin ZhangJoo SongWing C ChanTanya SiddiqiSteven T RosenAlexey DanilovLili Wang

Published in: bioRxiv : the preprint server for biology (2023)

regulatory axis is essential to the CLL-to-RT transition via modulation of mitochondrial OXPHOS, highlighting this pathway as a novel target for RT treatment.

Keyphrases

oxidative stress
transcription factor
replacement therapy
smoking cessation