Genetic determinants of renal scarring in children with febrile UTI.

Therese RosenbladMagnus LindénInes AmbitePer BrandströmSverker HanssonGabriela Godaly

Published in: Pediatric nephrology (Berlin, Germany) (2024)

In this nationwide study of genetic susceptibility to RS after febrile UTIs in infancy, we identified a profile dominated by mitochondrial polymorphisms. This profile can serve as a predictor of future complications, including RS and recurrent UTIs.

Keyphrases

urinary tract infection
genome wide
oxidative stress
copy number
young adults
risk factors
current status
dna methylation
gene expression