Pre-diagnostic C-reactive protein concentrations, CRP genetic variation and mortality among individuals with colorectal cancer in Western European populations.

Katharina NimptschKrasimira AleksandrovaVeronika FedirkoMazda JenabMarc J GunterPeter D SiersemaKana WuVerena KatzkeRudolf KaaksSalvatore PanicoDomenico PalliAnne M MaySabina SieriBas Bueno-de-MesquitaKarina StandahlMaria-Jose SánchezAurora Perez-CornagoAnja OlsenAnne TjønnelandCatalina Bonet BonetChristina C DahmMaría-Dolores ChirlaqueValentina FianoRosario TuminoAurelio Barricarte GurreaMarie-Christine Boutron-RuaultFlorence MenegauxGianluca SeveriBethany van GuelpenYoung-Ae LeeTobias Pischon

Published in: BMC cancer (2022)

The results of this prospective cohort study do not support a role of pre-diagnostic CRP concentrations on mortality in individuals with CRC. The observed associations with rs1205 deserve further scientific attention.

Keyphrases

cardiovascular events
risk factors
working memory
south africa
type diabetes
coronary artery disease
genetic diversity