5-Hydroxymethylcytosine signatures in circulating cell-free DNA as diagnostic and predictive biomarkers for coronary artery disease.

Chaoran DongJiemei ChenJilin ZhengYiming LiangTao YuYupeng LiuFeng GaoJie LongHangyu ChenQianhui ZhuZilong HeSongnian HuChuan HeJian LinYida TangHaibo Zhu

Published in: Clinical epigenetics (2020)

Our results suggest that 5hmC markers derived from cfDNA can serve as effective epigenetic biomarkers for minimally noninvasive diagnosis and prediction of CAD.

Keyphrases

coronary artery disease
percutaneous coronary intervention
cardiovascular events
gene expression
coronary artery bypass grafting
genome wide
type diabetes
cardiovascular disease