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Transient cell stiffening triggered by magnetic nanoparticle exposure.

Jose Efrain PerezFlorian FageDavid PereiraAli Abou HassanSophie AsnaciosAtef AsnaciosClaire Wilhelm
Published in: Journal of nanobiotechnology (2021)
Overall, this work evidences that magnetic nanoparticle internalization, coupled to cytoskeleton remodeling, contributes to a change in the cell mechanical properties within minutes of their initial contact, leading to an increase in cell rigidity. This effect appears to be transient, reduced after hours and disappearing 24 h after the internalization has taken place.
Keyphrases
  • single cell
  • cell therapy
  • stem cells
  • molecularly imprinted
  • subarachnoid hemorrhage
  • simultaneous determination