Integrated Bioinformatics Analysis and Target Drug Prediction of Inflammatory Bowel Disease Co-existent Diabetes Mellitus.

Lili Yang Ning Wang Yutong Wang Wen Li Ziyang Kong Bin Zhang Yao-Yao Bian

Published in: Current computer-aided drug design (2024)

Our findings revealed the regulatory mechanism chain of critical gene MMP3, lncRNA CDKN2BAS, and PPAR pathway and provided potential therapeutic compound ZINC05905909 for drug therapy to treat comorbid IBD DM.

Keyphrases

bioinformatics analysis
transcription factor
copy number
glycemic control
genome wide
insulin resistance
ulcerative colitis
long non coding rna
single cell
type diabetes
drug induced
stem cells
gene expression
mesenchymal stem cells
bone marrow
genome wide identification
cell therapy