The role of CD8 + T lymphocytes in chronic obstructive pulmonary disease: a systematic review.

Maya WilliamsIan ToddLucy C Fairclough

Published in: Inflammation research : official journal of the European Histamine Research Society ... [et al.] (2020)

Not only is the number of CD8 + T-cells increased in COPD, these cells have increased capacity to exert effector functions and are likely to contribute to disease pathogenesis. Several mechanisms highlighted show promise for future investigation to consolidate current knowledge.

Keyphrases

induced apoptosis
chronic obstructive pulmonary disease
healthcare
cell cycle arrest
lung function
dendritic cells
current status
regulatory t cells
big data
oxidative stress
signaling pathway
cell death
machine learning
cystic fibrosis
cell proliferation