Evaluation of a rapid combination disc test (RCDT) for direct phenotypic detection of extended-spectrum β-lactamase production in E. coli from positive blood culture bottles.

Benjamin BerinsonNicole Degel-BrossmannFlaminia OlearoHannes G RoggenkampAnna BothMartin AepfelbacherMartin ChristnerHolger Rohde

Published in: The Journal of antimicrobial chemotherapy (2023)

RCDT is a reliable method for rapid ESBL detection in E. coli directly from positive blood cultures. RCDT might complement RAST to support antibiotic stewardship interventions and treatment decisions.

Keyphrases

loop mediated isothermal amplification
escherichia coli
sensitive detection
klebsiella pneumoniae
real time pcr
label free
physical activity
multidrug resistant
gram negative
quantum dots
replacement therapy