Clinical Outcomes in Children With Human Immunodeficiency Virus Treated for Nonsevere Tuberculosis in the SHINE Trial.

Chishala Chabala Eric WobudeyaMarieke M van der ZalmMonica KapasaPriyanka RaichurRobert MboiziMegan Palmer Aarti Avinash KinikarSyed HissarVeronica Mulenga Vidya MavePhilippa MusokeAnneke C Hesseling Helen M McIlleron Diana M Gibb Angela CrookAnna Turkovanull null

Published in: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America (2024)

We found no evidence of a difference in TB outcomes between 4 and 6 months of treatment for CWH treated for nonsevere TB. Irrespective of TB treatment duration, CWH had higher rates of mortality and hospitalization than their counterparts without HIV. Clinical Trials Registration. ISRCTN63579542.

Keyphrases

human immunodeficiency virus
mycobacterium tuberculosis
antiretroviral therapy
clinical trial
hepatitis c virus
hiv infected
hiv positive
young adults
type diabetes
emergency department
combination therapy
phase ii
pulmonary tuberculosis
metabolic syndrome