Aetiology and outcomes of sepsis in adults in sub-Saharan Africa: a systematic review and meta-analysis.
Joseph M LewisNicholas A FeaseyJamie RylancePublished in: Critical care (London, England) (2019)
Sepsis in sSA is dominated by HIV and tuberculosis, with poor outcomes. Optimal antimicrobial strategies, including the role of tuberculosis treatment, are unclear. Long-term outcome data are lacking. Standardised sepsis diagnostic criteria that are easily applied in low-resource settings are needed to establish an evidence base for sepsis management in sSA.
Keyphrases
- septic shock
- acute kidney injury
- intensive care unit
- hiv aids
- mycobacterium tuberculosis
- human immunodeficiency virus
- staphylococcus aureus
- hiv positive
- big data
- machine learning
- pulmonary tuberculosis
- metabolic syndrome
- type diabetes
- adverse drug
- adipose tissue
- skeletal muscle
- insulin resistance
- deep learning
- weight loss
- replacement therapy
- smoking cessation
- drug induced