Pregnant Women Infected with Zika Virus Show Higher Viral Load and Immunoregulatory Cytokines Profile with CXCL10 Increase.
Elizabeth Camacho-ZavalaClara Santacruz-TinocoJosé Esteban Muñoz-MedinaRommel Chacón-SalinasMa Isabel Salazar-SanchezConcepción GrajalesJoaquin González-IbarraVictor Hugo Borja-AburtoThomas JaenischCesar Raúl González-BonillaPublished in: Viruses (2021)
Our results revealed a systemic anti-inflammatory cytokine and chemokine profile that could participate in the control of the virus. The anti-inflammatory response in pregnant women infected with ZIKA was characterized by high CXCL10, a cytokine that has been correlated with congenital malformations.