Serum Estradiol and 20 Site-Specific Cancers in Women: Mendelian Randomization Study.

Susanna C LarssonSiddhartha KarJohn R B PerryPaul CarterMathew VithayathilAmy M MasonDouglas F EastonStephen Burgess

Published in: The Journal of clinical endocrinology and metabolism (2021)

This study supports a role of E2 in the development of estrogen receptor positive breast cancer and endometrioid endometrial cancer, but found no strong association with other cancers in women.

Keyphrases

endometrial cancer
estrogen receptor
positive breast cancer
polycystic ovary syndrome
type diabetes
pregnancy outcomes
adipose tissue
insulin resistance