Compensated Hypogonadism Identified in Males with Cluster Headache: A Prospective Case-Controlled Study.

Anja Sofie PetersenDavid M KristensenConnar Stanley James Westgate Thomas Folkmann HansenNunu LundMads BarloeseMarie-Louise K SøborgAgneta SnoerTrine H JohannsenHanne FrederiksenAnders JuulRigmor H Jensen

Published in: Annals of neurology (2024)

Our results demonstrate that the male endocrine system is altered in patients with cluster headache to a state of compensated hypogonadism, and this is not an epiphenomenon associated with sleep or the use of acute medication. Together with the identified shared genetic risk allele, this may suggest a pathophysiological link between cluster headache and fT. ANN NEUROL 2024;95:1149-1161.

Keyphrases

replacement therapy
liver failure
healthcare
genome wide
emergency department
gene expression
depressive symptoms
copy number
acute respiratory distress syndrome