Genomic features of predominant non-PCV13 serotypes responsible for adult invasive pneumococcal disease in Spain.
Aida González-DíazDàmaris BerbelMaría ErcibengoaEmilia CercenadoNieves LarrosaMª Dolores QuesadaAntonio CasabellaMeritxell CuberoJosé María MarimónM Ángeles DomínguezAnna Carrera-SalinasJordi CàmaraAntonio J Martín-GalianoJose YusteSara MartiCarmen ArdanuyPublished in: The Journal of antimicrobial chemotherapy (2022)
We identified highly clonal predominant serotypes responsible for IPD in adults. The detection of not only conjugative elements carrying resistance determinants but also clones previously associated with vaccine serotypes (CC15611A and CC23024F) highlights the importance of the accessory genome.